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So, if you have reached this article you surely be curious about- Why is Tramadol prescribed?, What are the Side effects of Tramadol? , What Precautions should be taken while taking Tramadol? Buy tramadol online without prescription etc. There are times when we all have pain in our body, maybe due to injuries like- fracture, accident, and any kind of trauma or due to any other etiology which is unbearable for us and our physician prescribes Tramadol.

Let me tell you, that your search ends here, this article will give all the complete information about the widely used analgesic/painkiller- Tramadol in a very precise way under the following headings

Table of Contents

 Why is Tramadol prescribed?-Tramadol Uses:

 Other uses for Tramadol:

 How Tramadol Works? -Mechanism of action:

 What is the Safe Dose for Tramadol?-Dosage:

 Mode of administration:

 Direction of Usage:

 What are the Side effects of Tramadol?

 Common side-effects:

 Rare side effects:

 When one should not take Tramadol?- Contraindications?

 What should be avoided while taking Tramadol?

 What are the Drug interactions related to Tramadol?

 What Precautions should be taken while taking tramadol?

 What to do In case of Tramadol emergency/overdose?

 What is Available brands/Alternatives of Tramadol?

 FREQUENTLY ASKED QUESTIONS FOR TRAMADOL.

Why is Tramadol prescribed?-Tramadol Uses: 

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It is one of the most widely used painkillers. Precisely, it is a centrally acting opioid analgesic that helps in relieving mild to moderate pain.

It is commonly prescribed to those patients who had gone some surgery, any medical procedure, or due to any injury, trauma, or due to pain in the body that the patient can not bear easily.

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Other uses for Tramadol:

Apart from using as an analgesic Tramadol is also used in

 Continuous Backache

 Patients with Slip disc problems

 Treatment of Painful Sensory Neuropathies(i.e. Diabetic Neuropathy)

 Chronic pain(including cancer pain)

 NOTE: Tramadol is not effective in severe pain

How Tramadol Works? -Mechanism of action:

In simple words, Tramadol works by hindering/blocking the transmission of pain sensation to our brain, thus decreasing the perception of pain.

Let’s have a pharmacological aspect:

Active Ingredients in Tramadol–

Is Synthetic codeine(a natural alkaloid obtained from morphine).

Tramadol relieves pain by two mechanisms:

1. Opioid mechanism:

Tramadol(codeine) shows actions by interacting with opioid receptors present in our body. There are 3 types of opioid receptors namely -µ(mu), k(kappa), δ(delta), which are located at spinal, supraspinal, peripheral nerves, and stimulation/suppression of these receptors produces action like- Analgesia(due to which pain is relieved), respiratory depression, sedation, dependence, euphoria, decrease gastric motility, etc.

The main advantage of using Tramadol is- Its affinity for µ opioid receptor is low, while that fork(kappa) and δ(delta) are very low, which makes it suitable for relieving mild to moderate pain and less prone to other unwanted actions of codeine like- severe respiratory depression, sedation, etc.

2. Additional mechanism:

Unlike other opioids, it inhibits the reuptake of NA and 5-HT, increases the 5-HT release, and thus activates monoaminergic(i.e. involving monoamine neurotransmitters) spinal inhibition of pain.

Reversal of its action: Its analgesic action is only partially reversed by the opioid antagonist naloxone.

Buy tramadol online without prescriptionWhat is the Safe Dose for Tramadol? -Dosage:

It should be taken as directed by your physician.

Generally, for mild to moderate pain, it is prescribed as follows to children above the age of 12years and adults: 50- 100 mg: Twice daily(morning or evening) and if the pain still does not subsides your doctor may increase the dose up to 150 to 200 mg twice daily.

You can get prescribed for it by your doctor or buy tramadol online without prescription and save your time and money.

(NOTE: Maximum dosage should not increase 300 mg per day)

What can be the Mode of administration?

Tramadol can be taken in various forms:

Orally

Tablet, coated-Available as 50 mg

Tablet, film-coated

available as 50 mg

Tablet, extended-release- Available as 50 mg, 75 mg, 100 mg, 150 mg, 200 mg, 300 mg

Extended-release capsule- Available as 50 mg

Parenterally(Intravenous or Intramuscular injection)

For instant action I.V. /I.M. Tramadol can be given.

Generally, slow intravenous injection or diluted in solution Inj. is used.

100mg of I.V. tramadol is equianalgesic to 10 mg of morphine.

Available as ampoule-contains 100mg Tramadol hydrochloride in 2ml solution (50mg/ml)

What is the Direction of Usage?

Oral- Tablet/capsules should be administered as a whole, it should not be crushed/split/dissolved/chewed/snorted.

Parenteral– the infusion should be freshly prepared and used immediately or within 24 hrs. only if stored at 2 to 8°C refrigeration. Ampule should be used within sterile conditions.

What are the Side effects of Tramadol?

Generally, Tramadol is well tolerated in most of the patients, with mild side effects.

Common side-effects:

 Dizziness

 Constipation

 Headache

 Vertigo

 Dry mouth

 Changes in mood

 Heartburn or indigestion

NOTE: Every medicine have some or the other side effects due to its action on the body but this does not mean it will harm you or be fatal to your body, keep in mind that your doctor knows that its benefits are much more than its the risk of its side effects. Remember these are mild side effect which goes easily as soon as the medication course completes.

Rare side effects:

NOTE: Depending upon your body there if you show some side effects given below you should IMMEDIATELY consult your doctor or buy tramadol online without prescription.

 Fainting/Loss of consciousness

 Fast/irregular heartbeat,

 severe dizziness,

 Seizure

 Hives

 Rash

 Blisters

 Difficulty swallowing or breathing

 swelling of the face, or any body part.

When one should not take Tramadol?- Contraindications:

It is strictly advised that Tramadol should not be taken in following conditions:

 Head Injuries

 Allergies

 Epilepsy

 Breathing disorders

 Kidney diseases

 Liver diseases

 Mood disorders

 Substance used disorders

 Difficulty in urinating

 Intestinal problems(paralytic ileus)

 Breastfeeding

 Pregnant women

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What should be avoided while taking Tramadol?

 Activities involving high attention/alertness like Driving, operating heavy machinery, etc. should be avoided because tramadol can cause sleepiness and tiredness which may increase the chances of casualties.

 Avoid drinking alcohol- as it causes further suppression of brain activity thus showing severe harmful effects like increased sleepiness, aggravate dependence, loss of consciousness, etc.

What are the Drug interactions of Tramadol?

Tramadol shows various drug interactions amongst which most of them lead to severe adverse effects, so it becomes very important to inform your physician about other medications that you are taking.

Some of the drug interactions are given below:

Tramadol Interactions with Anti-depressants[UNSAFE]: Taking tramadol with drugs having the same actions for instance drugs like –other opioid painkiller or cough suppressants like– codeine, hydrocodone, etc. can increase severe side effects – depressed breathing, loss of consciousness, severe drowsiness.

Serotonin syndrome: Tramadol being a serotonergic drug(that increases serotonin) should not be given to the patients which are on SSRI therapy as it may cause “Serotonin syndrome/toxicity”– which can show serious adverse effects like-agitation, restlessness, rigidity, hyperthermia, delirium, sweating, twitchings followed by convulsions.

Avoid taking with MAO inhibitors: this shows severe ill effects. (some examples- isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, rasagiline, etc.)

 Taking tramadol with drugs having the same actions for instance drugs like –other opioid painkillers or cough suppressants like– codeine, hydrocodone, etc. can increase severe side effects – depressed breathing, loss of consciousness, severe drowsiness.

Tramadol Interactions with Food[SAFE]: Tramadol can be taken with food, food does not have a significant effect on tramadol pharmacotherapy.

Tramadol Interactions with Alcohol[UNSAFE]: Avoid drinking alcohol- as it causes further suppression of brain activity thus showing severe harmful effects- like increased sleepiness, aggravate dependence, loss of consciousness, etc.

What Precautions should be taken while Taking?

We all know that precaution is better than cure so following precautions should be kept in mind while taking Tramadol,before you buy tramadol online without prescription.

Previous Drug history: Always inform the physician about the complete history of medications that you are taking, so you can avoid any unwanted effects from drug interaction.

In Younger Population– Utmost precaution should be taken for children less than the age of 12 years should not take this as it may cause psycho-physiologic effect, seizures, dependency syndrome, etc.

In Older Adults Population- with various other comorbid conditions like-kidney, liver, breathing problems) is more prone to its side effects- like severe Drowsiness, shallow breathing, confusion, etc.

In Pregnant women– One should avoid taking tramadol during pregnancy, without Risk/Benefit assessment by a doctor, as it can cause harmful effects on the unborn.

Breastfeeding mother– Should avoid taking it because the drug may reach the newborn through the milk and can cause serious side effects like- neonatal withdrawal syndrome, decreased breathing, drowsiness, etc. which will affect the normal development of the infant.

In Alcohol addicts: Drinking alcohol with ongoing tramadol medication will lead to serious other complications as alcohol and tramadol both are CNS depressants which will further decrease the brain activity to such an extent that may result in dangerous health problems like- respiratory failure, alteration in heart rate, seizures, coma, death.

A combination of alcohol and tramadol causes elevated euphoric effects but this combination is strictly contradicted because it causes serious liver damage.

What to do In case of Tramadol emergency/overdose?

 Normal maximum dosage:

Maximum dose in a day should not exceed 300mg.

 Symptoms of an overdose of Tramadol:

Beyond the maximum dose Tramadol can cause serious health issues like- Seizures, Sedation, Respiratory depression, Urinary retention, Unconsciousness, etc.

What to do if you overdose on Tramadol?

Immediately seek medical help if the patient have-difficulty in breathing, loss of, seizures, Fainting, Loss of consciousness, Fast/irregular heartbeat, severe dizziness, Seizure, Hives, Rash, Blisters, etc.

It is advised while taking tramadol you should always keep a dose of Naloxone- an opioid antagonist with you which can reverse the effect of Tramadol. It works by blocking the effect of tramadol on the body which will prevent further increase in the opiate level in the blood.

Along with it, you should also inform your family members, or the persons who are frequently around(caregivers), that if they observe any unusual symptoms of overdose they can follow the emergency protocols, call for medical help, and until the help arrives give you at least a dose Naloxone so as it can save you from serious health problems.

What is Available brands/Alternatives of Tramadol?

TRAMADOL Brand Names:

 Tramazac Zydus Cadila

 Contramal Abbott

 Trd Modi Mundi Pharma Pvt Ltd.

 Domadol Torrent Pharmaceuticals Ltd

 Tramasure Mankind Pharma Ltd

 Tramadin Mankind Pharma Ltd

 Tramot Bennet Pharmaceuticals Limited

 Supridol Neon Laboratories Ltd

 Tramazac HP Zydus Cadila

Other brands names:

 Conzip

 Rybix ODT

 Ryzolt

 Ultram

 UltramER

Brands With combination:

Ultracet® (containing Acetaminophen, Tramadol)

FREQUENTLY ASKED QUESTIONS FOR TRAMADOL:

Do I require a prescription for taking Tramadol?

Yes, you require a prescription from an RMP for taking Opioid analgesics.

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What special dietary instructions should I follow?

There as such no special dietary instructions for taking tramadol, you can take it with your normal diet. Some say you can it any time irrespective of the food, but it is advisable to take it with food, eat dietary fibers, drink enough water so it does not upset your stomach, and may lead to constipation, acid reflux, other gastric problems.

You should keep these point before you buy tramadol online without prescription.

Is tramadol addictive?

Intake of tramadol for a short duration of time will not cause any significant dependence on the drug, it should not be used more than 5 days.

What will happen after the Prolonged use of tramadol?

Risks of long-term opioid use include hypersensitivity to pain, hypogonadism, and dependency. and fecal impaction is other risks due to CNS depression.

Is it safe to drive vehicles after taking Tramadol?

No, one should avoid driving vehicles and other heavy machinery, because it can increase the chances of falls, fractures, driving accidents, etc.

Is tramadol safe for diabetic patients?

In the latest researches* it had been found that tramadol can cause hypoglycemia(low blood sugar level) so patients on diabetes medications or any persons with low blood sugar should discuss this with his physician.

*“Physicians need to be aware that the use of tramadol may be associated with an increased risk of severe hypoglycemia,” said co-author Laurent Azoulay, an assistant professor in the department of oncology at McGill University in Montreal.”

Is tramadol safe for Blood pressure patients?

Generally when taken in the prescribed dose as it does not cause any significant change in the BP. But when taken in Overdose being a CNS depression it alters the heart rate so one with low blood pressure should be cautious with its use. So, always inform your physician about any heart problems or if you are on any Anti-hypertensive drug so as he can regulate the dose.

Is it prescribed to patients above 60 years of age?

If you have been prescribed Tramadol and you are an elderly patient you should take it under proper monitoring and management with utmost precaution. You can buy tramadol online without prescription but before that you should know your proper dosage.

The following precautions should be kept in mind:

 Start from low doses and do not abruptly stop the medicine.

 monitoring of Na(sodium) is important.

 Respiratory Monitoring should be done, to keep a check on Respiratory depression.

 Avoid Extended-release formulations as it causes prolonged effects. and can cause urinary retention.

 Psychic symptoms should also be monitored as it can cause severely confused states, falls, decreased alertness, etc.

What should I do if I missed a dose?

If you missed the dose as scheduled by your physician, you can take the when you remember but do not take 2 doses at the same time, there should be at least 4-6 hrs. the gap between two doses, otherwise skip the missed dose and continue the next dose.

What to do if I consumed Expired Medication?Buy tramadol online without prescription

Consuming a single dose of tramadol will not affect an individual that much, but if you develop some hypersensitivity reaction immediately contact your doctor.

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What should I know about storage and disposal of this medication?

 Store in a cool and dry place away from moisture, do not refrigerate, keep out of reach of children.

 Expired and unused medications should be disposed of carefully so as it not consumed by pets or others accidentally.

 For proper disposal, you can also contact your nearby pharmacist or read about the disposal method given by U.S. F.D.A.

What are OTC pain-relieving medications that I can have?

 Acetaminophen (Tylenol)

 Naproxen

 Ibuprofen(NSAID)-Motrin, Advil

To Know about more medication which can help you,Click on the links given below:

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Is it possible to buy valium online without prescription?

 VALIUM is a prescription medicine used to treat anxiety disorders for the short-term relief of the symptoms of anxiety to relieve the symptoms of alcohol withdrawal. It also include agitation, shakiness (tremor), sudden and severe mental or nervous system changes (delirium tremens), and seeing or hearing things that others do not see or hear (hallucinations) along with other medicines for the relief of muscle spasms along with other drugs to treat seizure disorders. You can buy valium online without prescription. First, you should consult your doctor about the dosage then you can easily order valium online.

 VALIUM is a federally controlled substance (C-IV) because it can be abused or lead to dependence. Keep VALIUM in a safe place to prevent misuse and abuse. Selling or giving away VALIUM may harm others, and is against the law.

Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use VALIUM for a condition for which it was not prescribed. Do not give VALIUM to other people, even if they have the same symptoms that you have. It may harm them. You can ask your pharmacist or healthcare provider for information about VALIUM that is written for health professionals then buy valium online without prescription.

Tell your healthcare provider if you have abused or been dependent on alcohol, prescription medicines, or street drugs.

  •  It is not known if VALIUM is safe and effective in children under six months of age.
  • It is not known if VALIUM is safe and effective for use longer than four months.

Information for Patients

To assure the safe and effective use of benzodiazepines, patients should be informed that, since benzodiazepines may produce psychological and physical dependence, they should consult with their physician before either increasing the dose or abruptly discontinuing this drug. The risk of addiction increases with the duration of treatment; it is also greater in patients with a history of alcohol or drug abuse. Patients should be advised against the simultaneous ingestion of alcohol and other CNS-depressant drugs during Valium therapy. As is true of most acting drugs, patients receiving Valium should be cautioned against engaging in hazardous occupations requiring complete mental alertness, such as operating machinery or driving a motor vehicle.

What is the most important information I should know about VALIUM?

  • VALIUM is a benzodiazepine medicine. Taking benzodiazepines with opioid medications, alcohol, or other central nervous system depressants (including street drugs) can cause severe drowsiness, breathing problems (respiratory depression), coma, and death.
  • VALIUM can make you sleepy or dizzy and can slow your thinking and motor skills.
  1. Do not drive, operate heavy machinery, or do other dangerous activities until you know how VALIUM affects you.
  2. Do not drink alcohol or take other drugs that may make you sleepy or dizzy while taking VALIUM without first talking to your healthcare provider.

When taken with alcohol or drugs that cause sleepiness or dizziness, VALIUM may make your drowsiness or dizziness much worse.

  • Do not take more VALIUM than prescribed.

Before you take VALIUM, tell your healthcare provider about all of your medical conditions, including if you:

  • have or have had depression, mood problems, or suicidal thoughts or behaviour
  • have lung disease or breathing problems
  • have liver or kidney problems
  • are pregnant or plan to become pregnant. VALIUM may harm your unborn baby.

You and your healthcare provider should decide if you should take VALIUM while you are pregnant are breastfeeding or plan to breastfeed.

VALIUM passes into your breast milk and may harm your baby. Talk to your healthcare provider about the best way to feed your baby if you take VALIUM.

Do not breastfeed while taking VALIUM. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Taking VALIUM with certain other medicines can cause side effects or affect how okay VALIUM or the other drugs work. Do not start or stop other medicines without talking to your healthcare provider. Before you buy valium online without prescription, you should be aware of its side effects properly.

Buy Valium online without prescriptionHow should I take VALIUM?

  • Take VALIUM precisely as your healthcare provider tells you to take it. Your healthcare provider will tell you how much VALIUM to take and when to take it.
  • Talk to your healthcare provider about slowly stopping VALIUM from avoiding withdrawal symptoms.
  • If you take too much VALIUM, call your healthcare provider or go to the nearest hospital emergency room right away.

What should I avoid while taking VALIUM?

  • VALIUM can cause you to be drowsy. Do not drive a car or operate heavy machinery until you know how VALIUM affects you.
  • It would help if you did not drink alcohol while taking VALIUM. Drinking alcohol can increase your chances of having severe side effects.

If you want to buy valium online without prescription, then you have to keep all these points in mind before consuming it.

What are the possible side effects of VALIUM?

VALIUM may cause serious side effects, including:

  • See “What is the most important information I should know about VALIUM?”
  • Seizures. Taking VALIUM with other medicines used to treat epilepsy can cause an increase in the number or severity of grand mal seizures.
  • Withdrawal symptoms. You may have withdrawal symptoms if you stop taking VALIUM suddenly. Withdrawal symptoms can be severe and include seizures. Mild withdrawal symptoms include a depressed mood and trouble sleeping.

Talk to your healthcare provider about slowly stopping VALIUM from avoiding withdrawal symptoms.

  • Like other antiepileptic drugs, VALIUM may cause suicidal thoughts or actions in a minimal number of people, about 1 in 500.

 Call your healthcare provider right away if you have any of these symptoms, especially if they are new, worse, or worry you: 

  •  thoughts about suicide or dying
  •  new or worse anxiety
  • trouble sleeping (insomnia)
  • acting on dangerous impulses
  • attempts to commit suicide
  • feeling agitated or restless
  • new or worse irritability
  • an extreme increase in activity and talking (mania)
  • new or worse depression
  • panic attacks
  • acting aggressive, being angry, or violent
  • Other unusual changes in behaviour or mood.

How can I watch for early symptoms of suicidal thoughts and actions?

  • Pay attention to any changes, especially sudden changes, in mood, behaviours, thoughts, or feelings. Keep all follow-up visits with your healthcare provider as scheduled.

Call your healthcare provider between visits as needed, especially if you are worried about symptoms. Suicidal thoughts or actions can be caused by things other than medicines. If you have suicidal thoughts or actions, your healthcare provider may check for other causes. 

  • Abuse and dependence. Taking VALIUM can cause physical and psychological support. Physical and psychological dependence is not the same as drug addiction. Your healthcare provider can tell you more about the differences between physical and mental dependence and drug addiction.

The most common side effects of VALIUM include:

  • drowsiness
  • muscle weakness
  • fatigue
  • loss of control of body movements (ataxia) These are not all the possible side effects of VALIUM.

Call your doctor for medical advice about side effects.

Basic Description- buy valium online without prescription

Valium (diazepam) is a benzodiazepine derivative. The chemical name of diazepam is 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin2-one. It is a colourless to light yellow crystalline compound, insoluble in water. The empirical formula is C16H13ClN2O, and the molecular weight is 284.75. 

The structural formula is as follows:

 Valium is available for oral administration as tablets containing 2 mg, 5 mg, or 10 mg diazepam. In addition to the active ingredient diazepam, each tablet contains the following inactive ingredients: anhydrous lactose, corn starch, pregelatinized starch, and calcium stearate with the following dyes: 5-mg tablets have FD&C Yellow No. 6 and D&C Yellow No. 10; 10-mg tablets contain FD&C Blue No. 1. Valium 2-mg tablets contain no pigment.

CONTRAINDICATIONS

Valium is contraindicated in patients with a known hypersensitivity to diazepam and, because of lack of sufficient clinical experience, in pediatric patients under six months of age. It is also contraindicated with myasthenia gravis, severe respiratory insufficiency, severe hepatic insufficiency, and sleep apnea syndrome. It may be used with open-angle glaucoma who are receiving appropriate therapy but are contraindicated in acute narrow-angle glaucoma.

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OVERDOSAGE

Overdose of benzodiazepines is usually manifested by central nervous system depression ranging from drowsiness to coma. In mild cases, symptoms include drowsiness, confusion, and lethargy. In more severe cases, symptoms may include ataxia, diminished reflexes, hypotonia, hypotension, respiratory depression, coma (rarely), and death (very rarely). Overdose of benzodiazepines in combination with other CNS depressants (including alcohol) may be fatal and should be closely monitored.

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PRECAUTIONS

General Precaution about Valium- Buy Valium Online without prescription

 Suppose Valium is to be combined with other psychotropic agents or anticonvulsant drugs. In that case, careful consideration should be given to the pharmacology of the agents to be employed – particularly with known compounds that may potentiate the action of diazepams, such as phenothiazines, narcotics, barbiturates, MAO inhibitors, and other antidepressants. The usual precautions are indicated for severely depressed patients or those in whom there is any evidence of latent depression or anxiety associated with depression, particularly the recognition that suicidal tendencies may be present and protective measures may be necessary. 

Psychiatric and paradoxical reactions are known to occur when using benzodiazepines. Should this occur, the use of the drug should be discontinued. These reactions are more likely to occur in children and the elderly. A lower dose is recommended for patients with chronic respiratory insufficiency due to the risk of respiratory depression. 

Benzodiazepines should be used with extreme caution in patients with a history of alcohol or drug abuse. In debilitated patients, it is recommended that the dosage be limited to the smallest sufficient amount to preclude the development of ataxia or oversedation (2 mg to 2.5 mg once or twice daily, initially, to be increased gradually as needed and tolerated). Some loss of response to the effects of benzodiazepines may develop after repeated use of Valium for a prolonged time.

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OXYCODONE (oxycodone hydrochloride tablets USP) is an opioid analgesic.
Each tablet for oral administration contains 15 mg or 30 mg of oxycodone hydrochloride USP. Oxycodone hydrochloride is a white, odorless crystalline powder derived from the opium alkaloid, thebaine. The analgesic ingredient, oxycodone, is a semi-synthetic narcotic with multiple actions.It is qualitatively similar to those of morphine; the most prominent of these involve the central nervous system and organs composed of smooth muscle.Now it’s easy to buy Oxycodone 30mg online from the internet.

Oxycodone hydrochloride dissolves in water (1 g in 6 to 7 mL) and is considered slightly soluble in alcohol (octanol-water partition coefficient is 0.7). Chemically, oxycodone hydrochloride is 4, 5α-epoxy-14-hydroxy-3-methoxy-17­ methyl morphinan-6-one hydrochloride.

Oxycodone, as the hydrochloride salt, is a pure agonist opioid whose principal therapeutic action is analgesia and has been in clinical use since 1917. Like all pure opioid agonists, there is no ceiling effect to analgesias, such as is seen with partial agonists or non-opioid analgesics. Based upon a single-dose, a relative-potency study conducted in humans with cancer pain. 10 to 15 mg of oxycodone given intramuscularly produced an analgesic effect similar to 10 mg of morphine given intramuscularly. Both drugs have a 3 to the 4-hour duration of action. Oxycodone retains approximately one half of its analgesic activity when administered orally.

INDICATIONS AND USAGE ( BUY OXYCODONE 30MG ONLINE )

Oxycodone tablets are an immediate-release oral formulation of oxycodone hydrochloride. It is indicated for the management of moderate to severe pain where the use of an opioid analgesic is appropriate. You should be aware about the dosage and precautions before you buy Oxycodone 30mg online.

DOSAGE AND ADMINISTRATION

OXYCODONE is intended for the management of moderate to severe pain in patients who require treatment with an oral opioid analgesic. The dose should be individually adjusted according to the severity of pain, patient response, and patient size. If the pain increases in severity, if analgesia is not adequate, or if tolerance occurs, a gradual increase in dosage may be required.

For control of severe chronic pain, OXYCODONE should be administered on a regularly scheduled basis, every 4-6 hours, at the lowest dosage level that will achieve adequate analgesia.

Patients who have not been receiving opioid analgesics should be started on OXYCODONE in a dosing range of 5 to 15 mg every 4 to 6 hours as needed for pain. The dose should be titrated based upon the individual patient’s response to their initial dose of OXYCODONE. Patients with chronic pain should have their dosage given on an around-the-clock basis to prevent the reoccurrence of pain rather than treating the pain Page 14 of 17 after it has occurred. This dose can then be adjusted to an acceptable level of analgesia taking into account side effects experienced by the patient.

As with any potent opioid, it is critical to adjust the dosing regimen for each patient individually, taking into account the patient’s prior analgesic treatment experience. Although it is not possible to list every condition that is important to the selection of the initial dose of OXYCODONE, attention should be given to

1) the daily dose, potency, and characteristics of a pure agonist or mixed agonist/antagonist the patient has been taking previously

2) the reliability of the relative potency estimate to calculate the dose of oxycodone needed,

3) the degree of opioid tolerance,

4) the general condition and medical status of the patient, and

5) the balance between pain control and adverse experiences.

 

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Drug Interactions:

Neuromuscular Blocking Agents: Oxycodone, as well as other opioid analgesics, may enhance the neuromuscular blocking action of skeletal muscle relaxants and produce an increased degree of respiratory depression. Oxycodone is metabolized in part to oxymorphone via the cytochrome p450 isoenzyme CYP2D6. While this pathway may be blocked by a variety of drugs (e.g., certain cardiovascular drugs and antidepressants), such blockade has not yet been shown to be of clinical significance with this agent. However, clinicians should be aware of this possible interaction.

CNS Depressants: Patients receiving narcotic analgesics, general anesthetics, phenothiazines, other tranquilizers, sedative-hypnotics, or other CNS depressants (including alcohol) concomitantly with OXYCODONE may exhibit an additive CNS depression. Interactive effects resulting in respiratory depression, hypotension, profound sedation, or coma may result if these drugs are taken in combination with the usual dosage of OXYCODONE. When such combined therapy is contemplated, the dose of one or both agents should be reduced.

OVERDOSAGE

Signs and Symptoms:
Acute overdose with OXYCODONE can be manifested by respiratory depression, somnolence progressing to stupor or coma, skeletal muscle flaccidity, cold and clammy skin, constricted pupils, bradycardia, hypotension, and death. Treatment: To treat OXYCODONE overdose, primary attention should be given to the reestablishment of a patent airway and institution of assisted or controlled ventilation. Supportive measures (including oxygen and vasopressors) should be employed in the management of circulatory shock and pulmonary edema accompanying overdose as indicated. Cardiac arrest or arrhythmias may require cardiac massage or defibrillation.

The narcotic antagonists, naloxone or nalmefene, are specific antidotes for opioid overdose. Opioid antagonists should not be administered in the absence of clinically significant respiratory or circulatory depression secondary to OXYCODONE overdose. If needed the appropriate dose of naloxone hydrochloride or nalmefene should be administered simultaneously with efforts at respiratory resuscitation (see package insert for each drug for the details). Since the duration of action of oxycodone may exceed that of the antagonist, the patient should be kept under continued surveillance and repeated doses of the antagonist should be administered as needed to maintain adequate respiration. Gastric emptying may be useful in removing unabsorbed drug.

DRUG ABUSE AND DEPENDENCE

Controlled Substance Roxicodone contains oxycodone, a mu-agonist opioid of the morphine type and is a Schedule II controlled substance. Oxycodone, like other opioids used in analgesia, can be abused and is subject to criminal diversion. Abuse Drug addiction is characterized by compulsive use, use for non-medical purposes, and continued use despite harm or risk of harm. Drug addiction is a treatable disease, utilizing a multi-disciplinary approach, but relapse is common.If your doctor consult you to consume Oxycodone then only you should buy Oxycodone 30mg online.

“Drug-seeking” behavior is very common in addicts and drug abusers. Drug-seeking tactics include emergency calls or visits near the end of office hours, refusal to undergo appropriate examination, testing or referral, repeated “loss” of prescriptions, tampering with prescriptions, and reluctance to provide prior medical records or contact information for other treating physician(s). “Doctor shopping” to obtain additional prescriptions is common among drug abusers and people suffering from untreated addiction.

Abuse and addiction are separate and distinct from physical dependence and tolerance. Physicians should be aware that addiction may not be accompanied by concurrent tolerance and symptoms of physical dependence. In addition, abuse of opioids can occur in the absence of true addiction and is characterized by misuse for nonmedical purposes, often in combination with other psychoactive substances. Careful record-keeping of prescribing information, including quantity, frequency, and renewal requests is strongly advised.

 

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Dependence

Tolerance is the need for increasing doses of opioids to maintain a defined effect such as analgesia (in the absence of disease progression or other external factors). Physical dependence is manifested by withdrawal symptoms after abrupt discontinuation of a drug or upon administration of an antagonist. Physical dependence and tolerance are not unusual during chronic opioid therapy.

The opioid abstinence or withdrawal syndrome is characterized by some or all of the following: restlessness, lacrimation, rhinorrhea, yawning, perspiration, chills, myalgia, and mydriasis. Other symptoms also may develop, including irritability, anxiety, backache, joint pain, weakness, abdominal cramps, insomnia, nausea, anorexia, vomiting, diarrhea, or increased blood pressure, respiratory rate, or heart rate. In general, opioids should not be abruptly discontinued.


Treatment:

To treat OXYCODONE® overdose, primary attention should be given to the reestablishment of a patent airway and institution of assisted or controlled ventilation. Supportive measures (including oxygen and vasopressors) should be employed in the management of circulatory shock and pulmonary edema accompanying overdose as indicated. Cardiac arrest or arrhythmias may require cardiac massage or defibrillation.If you want quick relief from all these problems then buy Oxycodone 30mg online now.

The narcotic antagonists, naloxone or nalmefene, are specific antidotes for opioid overdose. Opioid antagonists should not be administered in the absence of clinically significant respiratory or circulatory depression secondary to ROXICODONE® overdose. If needed the appropriate dose of naloxone hydrochloride or nalmefene should be administered simultaneously with efforts at respiratory resuscitation (see package insert for each drug for the details). Since the duration of action of oxycodone  may exceed that of the antagonist, the patient should be kept under continued surveillance and repeated doses of the antagonist should be administered as needed to maintain adequate respiration. Gastric emptying may be useful in removing unabsorbed drug.

ADVERSE REACTIONS ( BUY OXYCODONE 30MG ONLINE)

Oxycodone tablets have been evaluated in open-label clinical trials in patients with cancer and nonmalignant pain. OXYCODONE tablets are associated with adverse experiences similar to those seen with other opioids. Serious adverse reactions that may be associated with ROXICODONE® therapy in clinical use are those observed with other opioid analgesics and include: respiratory depression, respiratory arrest, circulatory depression, cardiac arrest, hypotension, and/or shock.

The following adverse experiences occurred in less than 3% of patients involved in clinical trials with oxycodone:
Body as a Whole: abdominal pain, accidental injury, allergic reaction, back pain, chills and fever, fever, flu syndrome, infection, neck pain, pain, photosensitivity reaction, and sepsis.

Cardiovascular: deep thrombophlebitis, heart failure, hemorrhage, hypotension, migraine, palpitation, and tachycardia.
Digestive: anorexia, diarrhea, dyspepsia, dysphagia, gingivitis, glossitis, and nausea and vomiting. Hemic and Lymphatic: anemia and leukopenia.
Metabolic and Nutritional: edema, gout, hyperglycemia, iron deficiency anemia, and peripheral edema.

Musculoskeletal: arthralgia, arthritis, bone pain, myalgia, and pathological fracture.
Nervous: agitation, anxiety, confusion, dry mouth, hypertonia, hypesthesia, nervousness, neuralgia, personality disorder, tremor, and vasodilation.

Respiratory: bronchitis, cough increased, dyspnea, epistaxis, laryngismus, lung disorder, pharyngitis, rhinitis, and sinusitis.

Skin and Appendages: herpes simplex, rash, sweating, and urticaria.
Special Senses: amblyopia. Urogenital: urinary tract infection

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About – Buy Klonopin Online legally (General Information)

Medicines are prescribed for purposes other than those listed in a Medication Guide. Do not use Klonopin for a condition for which it is unprescribed. Do not give Klonopin to other people, even if they have the same symptoms that you have. It may harm them. If you are having problem in buying Klonopin then you can buy Klonopin online legally.

This Medication Guide summarizes the essential information about Klonopin. If you would like more information, talk with your healthcare provider. You can ask your pharmacist or healthcare provider for information about Klonopin, written for health professionals. You can also surf the web about it and how you can buy Klonopin online legally.

Klonopin, a benzodiazepine, is available as scored tablets with a K-shaped perforation containing 0.5 mg of clonazepam and unscored tablets with a K-shaped perforation containing 1 mg or 2 mg of clonazepam. Each tablet also contains lactose, magnesium stearate, microcrystalline cellulose, and corn starch, with the following colorants: 0.5 mg—FD&C Yellow No. 6 Lake; 1 mg—FD&C Blue No. 1 Lake, and FD&C Blue No. 2 Lake. Chemically, clonazepam is 5-(2-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4­ benzodiazepine-2-one. It is a light yellow crystalline powder. It has a molecular weight of 315.72.

What is KLONOPIN? Buy Klonopin online legally.

Klonopin is a prescription medicine used alone or with other medicines to treat:

• certain types of seizure disorders (epilepsy) in adults and children

• panic disorder with or without fear of open spaces (agoraphobia) in adults

It is still unknown if Klonopin is safe or effective in treating panic disorder in children younger than 18.

Who should not take KLONOPIN?

Do not take KLONOPIN if you:

• are allergic to benzodiazepines

• have significant liver disease

• have an eye disease called acute narrow-angle glaucoma. Ask your healthcare provider if you are not sure if you have any of the problems listed above.

If you are taking or want to buy Klonopin online legally, you should consult about it with your doctor.

What should I tell my healthcare provider before taking KLONOPIN?

Before you take KLONOPIN, tell your healthcare provider if you:

• have liver or kidney problems

• have lung problems (respiratory disease) 

• have or have had depression, mood problems, or suicidal thoughts or behavior

• have any other medical conditions? Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Taking Klonopin with certain other medicines can cause side effects or affect how well they work. Details are all over the internet first, know the precautions about it, and then legally buy Klonopin. Do not start or stop other drugs without talking to your healthcare provider.

Know the medicines you take. Keep a list of them and show it to your healthcare provider and pharmacist when you get a new drug.

How should I take KLONOPIN? Buy Klonopin online legally.

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• Take KLONOPIN precisely as your healthcare provider tells you. KLONOPIN is available as a tablet.

• Do not stop taking KLONOPIN without first talking to your healthcare provider. Stopping KLONOPIN can cause serious problems.

• KLONOPIN tablets should be taken with water and swallowed whole.

• If you take too much KLONOPIN, call your healthcare provider or local Poison Control Center right away. What should I avoid while taking KLONOPIN?

• KLONOPIN can slow your thinking and motor skills. Do not drive, operate heavy machinery, or do other dangerous activities until you know how KLONOPIN affects you.

• Do not drink alcohol or take other drugs that may make you sleepy or dizzy while taking KLONOPIN until you talk to your healthcare provider.

When taken with alcohol or drugs that cause sleepiness or dizziness, KLONOPIN may worsen your drowsiness or dizziness. You can buy Klonopin online legally.

What are the possible side effects of KLONOPIN?

See “What is the most important information I should know about KLONOPIN?”

KLONOPIN can also make your seizures happen more often or make them worse.

Call your healthcare provider right away if your seizures get worse while taking KLONOPIN. The most common side effects of KLONOPIN include:

• Drowsiness

• Problems with walking and coordination

• Dizziness

• Depression

• Fatigue

• Problems with memory These are not all the possible side effects of KLONOPIN. For more information, ask your healthcare provider or pharmacist.

Dosage Information

Klonopin tablets are available as scored tablets with a K-shaped perforation – 0.5 mg, orange (NDC 0004-0068-01); and unscored tablets with a K-shaped perforation – 1 mg, blue (NDC 0004-0058-01); 2 mg, white (NDC 0004-0098-01) – bottles of 100.

Imprint on tablets:

0.5 mg – 1/2 KLONOPIN (front) ROCHE (scored side)

1 mg – 1 KLONOPIN (front) ROCHE (reverse side)

2 mg – 2 KLONOPIN (front) ROCHE (reverse side)

INDICATIONS AND USAGE- view online

Seizure Disorders: Klonopin is useful alone or as an adjunct in the treatment of the Lennox-Gastaut syndrome (petit mal variant), akinetic, and myoclonic seizures. Klonopin may help patients with absence seizures (petit mal) who have failed to respond to succinimides. Some studies show up to 30% of patients have shown a loss of anticonvulsant activity, often within three months of the administration. In some cases, dosage adjustment may reestablish efficacy.

Respiratory: Chest congestion, rhinorrhea, shortness of breath, hypersecretion in upper respiratory passages

Cardiovascular: Palpitations

Dermatologic: Hair loss, hirsutism, skin rash, ankle, and facial edema

Gastrointestinal: Anorexia, coated tongue, constipation, diarrhea, dry mouth, encopresis, gastritis, increased appetite, nausea, sore gums

Genitourinary: Dysuria, enuresis, nocturia, urinary retention

Musculoskeletal: Muscle weakness, pains

Miscellaneous: Dehydration, general deterioration, fever,

lymphadenopathy, weight loss or gain

Hematopoietic: Anemia, leukopenia, thrombocytopenia, eosinophilia

Panic Disorder: Klonopin is indicated for treating panic disorder, with or without agoraphobia, as defined in DSM-IV. Panic disorder is characterized by unexpected panic attacks and associated concern about having additional attacks, worry about the implications or consequences of the attacks, and a significant change in behavior related to the attacks. Klonopin’s efficacy was established in two 6- to 9-week trials in panic disorder patients whose diagnoses corresponded to the DSM-IIIR category of panic disorder.

Treatment-Emergent Depressive Symptoms:

In the pool of two short-term placebo-controlled trials, adverse events classified under the preferred term “depression” were reported in 7% of Klonopin-treated patients compared to 1% of placebo-treated patients, without any clear pattern of dose relatedness. In these same trials, adverse events classified under the preferred term “depression” were reported as leading to discontinuation in 4% of Klonopin-treated patients compared to 1% of placebo-treated patients. While these findings are noteworthy, Hamilton Depression Rating Scale (HAM-D) data collected in these trials revealed a more considerable decline in HAM-D scores in the clonazepam group than the placebo group suggesting that clonazepam treated patients were not experiencing a worsening or emergence of clinical depression.

The effectiveness of Klonopin in long-term use, that is, for more than nine weeks, has not been systematically studied in controlled clinical trials. The physician who elects to use Klonopin for extended periods should periodically reevaluate the drug’s long-term usefulness for the individual patient.

CONTRAINDICATIONS

You should not use Klonopin if you have a history of sensitivity to benzodiazepines, nor in patients with clinical or biochemical evidence of significant liver disease. You can use with open-angle glaucoma who are receiving appropriate therapy but are contraindicated in acute narrow-angle glaucoma.

Information for Patients: Buy Klonopin online legally

Pharmacists must give a guide to the patient each time Klonopin is dispensed, as required by law. Patients should be instructed to take Klonopin only as prescribed. Physicians are advised to discuss the following issues with patients for whom they prescribe Klonopin.

Dose Changes: To assure the safe and effective use of benzodiazepines, patients should be informed that, since benzodiazepines may produce psychological and physical dependence, they should consult with their physician before increasing the dose or abruptly discontinuing this drug.

Interference With Cognitive and Motor Performance: Because benzodiazepines have the potential to impair judgment, thinking, or motor skills, patients should be cautioned about operating hazardous machinery, including automobiles, until they are reasonably sure that Klonopin therapy does not affect them adversely.

Suicidal Thinking and Behavior: Doctors should consult the families of patients that AEDs, including Klonopin, may increase the risk of suicidal thoughts and behavior and should be advised of the need to be alert for the emergence or worsening of symptoms of depression, any unusual changes in mood or behavior, or the emergence of suicidal thoughts, action, or thoughts about self-harm. It would help if you informed immediately to healthcare providers.

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What is XANAX 2mg? – Buy Xanax 2mg online

Xanax Tablets contain alprazolam which is a triazole analog of the 1,4 benzodiazepine class of central nervous system active compounds. The chemical name of alprazolam is 8-Chloro-1-methyl-6-phenyl-4H-s-triazole [4,3-α] [1,4] benzodiazepine. Buy Xanax 2mg online and save your time & money.

The structural formula is represented to the right: Alprazolam is a white crystalline powder, which is soluble in methanol or ethanol but which has no appreciable solubility in water at physiological pH. Each XANAX Tablet, for oral administration, contains 0.25, 0.5, 1 or 2 mg of alprazolam. XANAX Tablets, 2 mg, are multi-scored and may be divided as shown below: Inactive ingredients: Cellulose, corn starch, docusate sodium, lactose, magnesium stearate, silicon dioxide, and sodium benzoate. Also, the 0.5 mg tablet contains FD&C Yellow No. 6 and the 1 mg tablet contains FD&C Blue No. 2.

CLINICAL STUDIES

Uses Of Xanax- ways to buy xanax 2mg online

Anxiety Disorders XANAX Tablets were compared to placebo in double-blind clinical studies (doses up to 4 mg/day) in patients with a diagnosis of anxiety or anxiety with associated depressive symptomatology. XANAX was significantly better than placebo at each of the evaluation periods of these 4-week studies as judged by the following psychometric instruments.
Physician’s Global Impressions, Hamilton Anxiety Rating Scale, Target Symptoms, Patient’s Global Impressions, and Self-Rating Symptom Scale.
Panic Disorder Support for the effectiveness of XANAX in the treatment of panic disorder came from three short-term, placebo-controlled studies (up to 10 weeks) in patients with diagnoses closely corresponding to DSM-III-R criteria for panic disorder.

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DOSAGE Of Xanax

Dosage should be individualized for maximum beneficial effect. While the usual daily dosages given below will meet the needs of most patients, there will be some who require doses greater than 4 mg/day. In such cases, the dosage should be increased cautiously to avoid adverse effects.

Dose Maintenance

In controlled trials conducted to establish the efficacy of XANAX XR Tablets in panic disorder, doses in the range of 1 to 10 mg/day were used. Most patients showed efficacy in the dose range of 3 to 6 mg/day. Occasional patients required as much as 10 mg/day to achieve a successful response.
The average dose of XANAX was 5-6 mg/day in two of the studies, and the doses of XANAX were fixed at 2 and 6 mg/day in the third study. In all three studies, XANAX was superior to placebo on a variable defined as “the number of patients with zero panic attacks” (range, 37­ 83% met this criterion), as well as on a global improvement score. In two of the three studies, XANAX was superior to placebo on a variable defined as “change from baseline on the number of panic attacks per week” (range, 3.3-5.2), and also on a phobia rating scale. A subgroup of patients who were improved on XANAX during short-term treatment in one of these trials was continued on an open basis for up to 8 months, without apparent loss of benefit.

CONTRAINDICATIONS of XANAX Tablets

Xanax Tablets are contraindicated in patients with known sensitivity to this drug or other benzodiazepines. XANAX may be used in patients with open-angle glaucoma who are receiving appropriate therapy but is contraindicated in patients with acute narrow-angle glaucoma. XANAX is contraindicated with ketoconazole and itraconazole since these medications significantly impair the oxidative metabolism mediated by cytochrome P450 3A.

Risk of Dose Reduction of Xanax

Withdrawal reactions may occur when dosage reduction occurs for any reason. This includes purposeful tapering, but also inadvertent reduction of dose (eg, the patient forgets, the patient is admitted to a hospital). Therefore, the dosage of XANAX should be reduced or discontinued gradually.

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For all users of XANAX: To assure safe and effective use of benzodiazepines, all patients prescribed XANAX should be provided with the following guidance.

1. Inform your physician about any alcohol consumption and medicine you are taking now, including medication you may buy without a prescription. Alcohol should generally not be used during treatment with benzodiazepines.

2. Not recommended for use in pregnancy. Therefore, inform your physician if you are pregnant, if you are planning to have a child, or if you become pregnant while you are taking this medication.
3. Inform your physician if you are nursing.

4. Until you experience how this medication affects you, do not drive a car or operate potentially dangerous machinery, etc.

5. Do not increase the dose even if you think the medication “does not work anymore” without consulting your physician. Benzodiazepines, even when used as recommended, may produce emotional and/or physical dependence.

6. Do not stop taking this medication abruptly or decrease the dose without consulting your physician, since withdrawal symptoms can occur.

Additional advice for panic disorder patients: Uses of Xanax

The use of XANAX at doses greater than 4 mg/day, often necessary to treat panic disorder, is accompanied by risks that you need to carefully consider. When used at doses greater than 4 mg/day, which may or may not be required for your treatment, XANAX has the potential to cause severe emotional and physical dependence in some patients and these patients may find it exceedingly difficult to terminate treatment. In two controlled trials of 6 to 8 weeks duration where the ability of patients to discontinue medication was measured, 7 to 29% of patients treated with XANAX did not completely taper off therapy. In a controlled postmarketing discontinuation study of panic disorder patients, the patients treated with doses of XANAX greater than 4 mg/day had more difficulty tapering to zero doses than patients treated with less than 4 mg/day. In all cases, your physician must help you discontinue this medication carefully and safely to avoid the overly extended use of XANAX.

Pediatric Use Safety and effectiveness of XANAX in individuals below 18 years of age have not been established.

Geriatric Use The elderly may be more sensitive to the effects of benzodiazepines. They exhibit higher plasma alprazolam concentrations due to reduced clearance of the drug as compared with a younger population receiving the same doses. The smallest effective dose of XANAX should be used in the elderly to preclude the development of ataxia and oversedation.

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DRUG ABUSE AND DEPENDENCE

Physical and Psychological

Dependence Withdrawal symptoms similar in character to those noted with sedative/hypnotics and alcohol have occurred following discontinuance of benzodiazepines, including XANAX. The symptoms can range from mild dysphoria and insomnia to a major syndrome that may include abdominal and muscle cramps, vomiting, sweating, tremors, and convulsions.
Distinguishing between withdrawal emergent signs and symptoms and the recurrence of illness is often difficult in patients undergoing dose reduction. The long term strategy for the treatment of these phenomena will vary with their cause and the therapeutic goal. When necessary, immediate management of withdrawal symptoms requires the re-institution of treatment at doses of XANAX sufficient to suppress symptoms.
There have been reports of failure of other benzodiazepines to fully suppress these withdrawal symptoms. These failures have been attributed to incomplete cross-tolerance but may also reflect the use of an inadequate dosing regimen of the substituted benzodiazepine or the effects of concomitant medications.

OVERDOSAGE- Buy Xanax 2mg Online

Manifestations of alprazolam overdosage include somnolence, confusion, impaired coordination, diminished reflexes, and coma. Death has been reported in association with overdoses of alprazolam by itself, as it has with other benzodiazepines. Also, fatalities have been reported in patients who have overdosed with a combination of a single benzodiazepine, including alprazolam, and alcohol; alcohol levels are seen in some of these patients have been lower than those usually associated with alcohol-induced fatality.You should not take overdose and if you want to buy xanax 2mg online without prescription then you should use it for good cause.

General Treatment of Overdose

Overdosage reports with XANAX Tablets are limited. As in all cases of drug overdosage, respiration, pulse rate, and blood pressure should be monitored. General supportive measures should be employed, along with immediate gastric lavage. Intravenous fluids should be administered and an adequate airway maintained. If hypotension occurs, it may be combated by the use of vasopressors. Dialysis is of limited value. As with the management of intentional overdosing with any drug, it should be borne in mind that multiple agents may have been ingested.

Information for Patients

To assure safe and effective use of XANAX XR, the physician should provide the patient with the following guidance.

1. Inform your physician about any alcohol consumption and medicine you are taking now, including medication you may buy without a prescription. Alcohol should generally not be used during treatment with benzodiazepines.

2. Not recommended for use in pregnancy. Therefore, inform your physician if you are pregnant, if you are planning to have a child, or if you become pregnant while you are taking this medication.

3. Inform your physician if you are nursing.

4. Until you experience how this medication affects you, do not drive a car or operate potentially dangerous machinery, etc.

5. Do not increase the dose even if you think the medication “does not work anymore” without consulting your physician. Benzodiazepines, even when used as recommended, may produce emotional and/or physical dependence.

6. Do not stop taking this medication abruptly or decrease the dose without consulting your physician, since withdrawal symptoms can occur.

7. Some patients may find it very difficult to discontinue treatment with XANAX XR due to severe emotional and physical dependence.

Discontinuation symptoms, including possible seizures, may occur following discontinuation from any dose, but the risk may be increased with extended use at doses greater than 4 mg/day, especially if discontinuation is too abrupt. You must seek advice from your physician to discontinue treatment carefully and safely. Proper discontinuation will help to decrease the possibility of withdrawal reactions that can range from mild reactions to severe reactions such as seizures.

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Adderall is a prescription medication used to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy. Adderall contains a combination of amphetamine and dextroamphetamine. Adderall is used to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy.You can buy cheap adderall online if your doctor consult you to consume adderall.

Adderall may also be used for purposes not listed in this medication guide. Adderall, a brand name, is a combination of amphetamine and dextroamphetamine, which are central nervous system stimulants. Taking Adderall may help increase the ability to focus, pay attention and control behavior. Adderall may be habit-forming, and this medicine is a drug of abuse.

Tell your doctor if you have had problems with drug or alcohol abuse. 

Adderall may cause new or worsening psychosis (unusual thoughts or behavior), especially if you have a history of depression, mental illness, or bipolar disorder.

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Uses of Adderall

Read the Medication Guide provided by your pharmacist before you start taking amphetamine/dextroamphetamine and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

This combination medication is used to treat attention deficit hyperactivity disorder – ADHD. It works by changing the amounts of certain natural substances in the brain.

The dosage is based on your medical condition and response to treatment.

The first dose is usually taken when you wake up in the morning. Take this medication by mouth with or without food as directed by your doctor, usually 1 to 3 times a day.

If more doses are prescribed, take them as directed by your doctor, usually 4-6 hours apart. Taking this medication late in the day may cause trouble sleeping (insomnia).

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.

Though it helps many people, this medication may sometimes cause addiction. This risk may be higher if you have a substance use disorder (such as overuse of or addiction to drugs/alcohol). Do not increase your dose, take it more often, or use it for a longer time than prescribed. Properly stop the medication when so directed.

Adderall may be habit-forming, and this medicine is a drug of abuse. You can easily buy cheap adderall online from the internet.

Warning for taking Adderall (buy cheap adderall online)

Do not use this medicine if you have used a MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, or tranylcypromine or have received a methylene blue injection.

If you take Adderall for ADHD, or for other purposes, it’s important to be aware of the side effects before you buy cheap adderall online. Effects can be positive when Adderall is taken as intended, but for people without ADHD who use the drug without medical supervision, the effects can be dangerous. Learn more about the range of effects this stimulant has on your body.

This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Avoid drinking fruit juices or taking vitamin C at the same time you take Adderall. These can make your body absorb less of the medicine.

Adderall can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using this medicine.

Common Adderall side effects may include:

  • stomach pain, loss of appetite;
  • weight loss;
  • mood changes, feeling nervous;
  • fast heart rate;
  • headache, dizziness;
  • sleep problems (insomnia); or
  • dry mouth.

If you suddenly stop using this medication, you may have withdrawal symptoms (such as severe tiredness, sleep problems, mental/mood changes such as depression).

To help prevent withdrawal, your doctor may lower your dose slowly. Withdrawal is more likely if you have used this medication for a long time or in high doses. Tell your doctor or pharmacist right away if you have withdrawal.

Dosage of Adderall- Buy cheap adderall online in USA

The dosage is based on your medical condition and response to treatment. Your doctor may adjust your dose to find the dose that is best for you. Follow your doctor’s instructions carefully.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.

During treatment, your doctor may occasionally recommend stopping the medication for a short time to see whether there are any changes in your behavior and whether the medication is still needed.

Adderall is available as a tablet and as an extended-release capsule (Adderall XR). It comes in varying doses, ranging from 5 mg to 30 mg. The prescribed dose will depend on the size of the patient and the severity of symptoms. Doctors typically start patients with a low dose and gradually increase the dose, according to the National Institutes of Health (NIH).

The tablet is usually taken two to three times daily and the extended-release capsule is usually taken once daily, according to the NIH.

Doses are different for different ages group so be carefull while taking it:

Age 6 to 11 Years:

-Initial Dose: 5 mg orally per day in divided doses

-Maintenance Dose: Daily dose may be raised in 5 mg increments at weekly intervals until optimal response is obtained.

Age 12 Years and Older:

-Initial Dose: 10 mg orally per day in divided doses

-Maintenance Dose: Daily dose may be raised in 10 mg increments at weekly intervals until optimal response is obtained.

Note:

-The first dose should be given on awakening; 1 to 2 additional doses should be given at intervals of 4 to 6 hours.

-The usual dose is 5 to 60 mg per day in divided doses, depending on the individual patient response.

-Dosage should be reduced if bothersome adverse reactions (e.g., insomnia, anorexia) appear.

-Narcolepsy rarely occurs in children under 12 years of age.

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Adderall is not for everybody. It should not be used by patients with a history of glaucoma, severe anxiety or agitation, a personal or family history of tics, or Tourette syndrome. Stimulants can also cause sudden death in patients with congenital heart defects or serious heart problems. As a result, patients should alert their doctors if they have a history of heart disease, heart rhythm disorder, coronary artery disease or heart attacks, according to the NIH. Doctors should also be alerted if the patient has a history of high blood pressure, mental illness, peripheral vascular disease or seizure disorders.

Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.

Call doctor as early as possible Get emergency medical help if you have signs of an allergic reaction to Adderall: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • signs of heart problems – chest pain, trouble breathing, feeling like you might pass out;
  • signs of psychosis – hallucinations (seeing or hearing things that are not real), new behavior problems, aggression, hostility, paranoia;
  • signs of circulation problems – numbness, pain, cold feeling, unexplained wounds, or skin color changes (pale, red, or blue appearance) in your fingers or toes;

Adderall can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using this medicine.

Common Adderall side effects may include:

Dextroamphetamine and amphetamine may cause side effects, including:

  • Nervousness
  • Restlessness
  • Difficulty falling asleep or staying asleep
  • Uncontrollable shaking of a part of the body
  • Headache
  • Changes in sex drive or ability
  • Dry mouth
  • Stomach pain
  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Loss of appetite
  • Weight loss

What should I avoid while taking Adderall?

For people diagnosed with attention-deficit hyperactivity disorder (ADHD), Adderall helps to improve concentration and focus. As a central nervous system stimulant it can also have the very same effects on people without ADHD. Adults ages 65 and older should usually not take Adderall because it is not as safe as other medications for this age group, the NIH says.

Adderall is not for everybody. It should not be used by patients with a history of glaucoma, severe anxiety or agitation, a personal or family history of tics, or Tourette syndrome. Stimulants can also cause sudden death in patients with congenital heart defects or serious heart problems.

If you take Adderall for ADHD, or for other purposes, it’s important to be aware of the side effects. Effects can be positive when Adderall is taken as intended, but for people without ADHD who use the drug without medical supervision, the effects can be dangerous. Learn more about the range of effects this stimulant has on your body. As a result, patients should alert their doctors if they have a history of heart disease, heart rhythm disorder, coronary artery disease or heart attacks, according to the NIH. Doctors should also be alerted if the patient has a history of high blood pressure, mental illness, peripheral vascular disease or seizure disorders.

Abuse and addiction to Adderall- Buy cheap adderall online

There is a rising trend of college students abusing Adderall and similar drugs, like Ritalin, to perform better on tests and papers. A study by the Substance Abuse and Mental Health Services Administration (SAMHSA) found that full-time college students were twice as likely as non-students to have used Adderall non-medically.

“Adderall has become one of the mainstay drugs at many party events both on [college] campus[es] and off because it is cheap and easy to access

Chronic abuse is marked by severe rash, insomnia, irritability and personality changes. The most severe symptom of abuse is psychosis, which is often clinically indistinguishable from schizophrenia, according to the FDA.

Toxic symptoms from taking an overdose of Adderall can come at low doses. Initial signs of an overdose include restlessness, tremor, confusion, hallucinations and panic, the FDA says. After this central stimulation, the patient will undergo fatigue, depression, and often cardiovascular and gastrointestinal symptoms. The NIH says that people should contact a medical professional immediately if they suspect that they or someone they know has overdosed on Adderall.

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SOMA: Buy Soma Muscle Relaxer

Carisoprodol (Soma) is a prescription drug marketed since 1959. It is a centrally acting muscle relaxant. The diversion and abuse of carisoprodol have increased in the last decade. Now you can buy soma muscle relaxer from the web easily.

What is Soma?

SOMA also know by the carisoprodol Tablets. Soma is a muscle relaxer medicine which is given only by prescription of doctors but you can also buy soma muscle relaxer online. Soma medicine that blocks pain sensations between the nerves and the brain. Muscle relaxers are also prescribed for other conditions such as fibromyalgia, multiple sclerosis, and seizure disorders.

 Soma is indicated for the relief of discomfort and relaxing associated with acute, painful musculoskeletal conditions in adults.

Soma should only be used for short periods (up to 2 or 3 weeks) because adequate evidence of effectiveness for more prolonged use has not been established and there is also no evidence of Soma effectiveness in long term use and most skeletal muscle injuries are generally of short duration painful muscle discomfort conditions are generally of short duration mostly

Uses of Soma?

You should not take Soma if you have extreme muscle (carisoprodol) pain, a genetic enzyme disorder that causes symptoms affecting the skin or nervous system or are allergic to carisoprodol.

DOSAGE

The standard dosage for adults is 350 mg three times daily and at bed-time. Use in patients under age 12 is not recommended. According to IMS Health™, there were approximately 10.58 million prescriptions for carisoprodol dispensed in 2008.

The recommended doctor prescribed taking dose of SOMA is 250 mg to 350 mg three times a day and at bedtime. The recommended maximum duration of SOMA use is up to two or three weeks. 250 to 350 mg orally 3 times a day and at bedtime. You should consult your doctor before you buy soma muscle relaxer

Duration of therapy: Up to 2 to 3 weeks

Soma drug should only be used for short periods. For the relief of discomfort associated with acute, painful musculoskeletal conditions.

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Soma may be prescribed to treat back pain:

  • Early in the course of back pain, on a short-term basis, to relieve pain associated with muscle spasms
  • When back pain causes insomnia (for their sedative effect)
  • Soma are also prescribed for other conditions such as fibromyalgia, multiple sclerosis, and seizure disorders.
  • Soma drug of muscle relaxer medications commonly used to treat back pain.

Chemical structure of Soma Drug

Chemically, carisoprodol is N-isopropyl-2-methyl-2-propyl-1,3propanediol dicarbamate and the molecular formula is C12H24N2O4, with a molecular weight of 260.33. The structural formula is:

SOMA also know by the carisoprodol Tablets are available as 250 mg and 350 mg round, white tablets. Carisoprodol is a white, crystalline powder, having a mild, characteristic odor and a bitter taste. It is slightly soluble in water; freely soluble in alcohol, in cholorform and in acetone; and its solubility is practically independent of pH.Carisoprodol is present as a racemic mixture.

Muscle relaxers are not a class of drugs—meaning they do not all have the same chemical structure or work the same way in the brain. Rather, the term muscle relaxer is used to describe a group of drugs that act as central nervous system depressants and have sedative and musculoskeletal relaxant properties.

Muscle relaxers may be prescribed to treat back pain:

  • Early in the course of back pain, on a short-term basis, to relieve pain associated with muscle spasms
  • When back pain causes insomnia for their sedative effect

Warnings for Soma prescription for muscle relax

Muscle relaxants such as Soma (carisoprodol) and can be habit forming. Be sure to take your medication exactly as prescribed by your doctor.

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Soma can also cause withdrawal symptoms, such as seizures or hallucinations sensing things that aren’t real. Do not suddenly stop taking your medication, especially if you’ve been taking it for a long time. All precautions should be followed before you buy soma muscle relaxer online.

Also, Soma depress your central nervous system (CNS), making it hard to pay attention or stay awake. While taking a muscle relaxant, avoid activities that require mental alertness or coordination, such as driving or using heavy machinery.

You should not take Soma drug with:

  • alcohol
  • CNS depressant drugs, such as opioids.
  • sleeping medications
  • herbal supplements

Talk to your doctor about how you can safely buy soma muscle relaxer drug if you:

  • are older than 65 years
  • have a mental health problem or brain disorder
  • have liver problems

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Soma Prescription medications

Prescription medications are divided into two groups: antispasmodics and antispastics. Antispasmodics are used to treat muscle spasms, and antispastics are used to treat muscle spasticity. Some antispasmodics, such as tizanidine, can be used to treat muscle spasticity. However, antispastics should not be used to treat muscle spasms.

Soma dosing information

250 mg Tablets: round, convex, white tablets, inscribed with SOMA 250

350 mg Tablets: round, convex, white tablets, inscribed with SOMA 350

Storage And Handling

250 mg Tablets: round, convex, white tablets, inscribed with SOMA 250; available in bottles of 100 (NDC 0037-2250-10) and bottles of 30 (NDC 0037-2250-30).

350 mg Tablets: round, convex, white tablets, inscribed with SOMA 350; available in bottles of 100 (NDC 0037-2001-01).

What are the side effects of soma?

Clinical studies are conducted under widely varying conditions, adverse reaction rates observed in clinical studies of soma cannot be directly compared to rates in the clinical studies of another drug and may not reflect rates observed in practice.

Allergic reaction may couse some time by soma so be carefull

An allergic reaction to Soma hives difficult breathing; swelling of your face, lips, tongue, or throat.

High levels of serotonin in the body – agitation, hallucinations, fever, sweating, shivering, increase in heart rate fast heart beatsmuscle stiffness, twitching, loss of coordination, nausea, vomiting, and ets.

For complete care in any side effects call some one Call your doctor for medical advice about side effects. You should be properly aware about all the side effects before you buy soma muscle relaxer online.

buy soma muscle relaxerMuscle pain or soma uses

 Buy Soma Muscle relaxer , or muscle relaxants, to treat muscle spasms or muscle spasticity. Muscle pain or cramps are sudden, involuntary contractions of a muscle or group of muscles. They can be caused by too much muscle strain and lead to pain. They’re associated with conditions such as lower back pain, neck pain. Muscle pain on the other hand, is a continuous muscle spasm that causes stiffness, rigidity, or tightness that can interfere with normal walking, talking, or movement. Muscle spasticity is caused by injury to parts of the brain or spinal cord involved with movement. Conditions that can cause muscle spasticity include multiple sclerosis (MS), cerebral palsy, and amyotrophic lateral sclerosis (ALS).

Prescription drugs can help relieve the pain and discomfort from muscle spasms or spasticity. In addition, certain over-the-counter medications may be used to treat aches and pains associated with muscle spasms.

 How should take Soma?

Take Soma exactly as doctor told and how it was prescribed for you. directions on your prescription label and read all medication guides or instruction sheets must be followed carefully.

Take the Soma as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. Overdose symptoms may include vision problems, confusion, hallucinations, muscle stiffness, loss of coordination, weak or shallow breathing, fainting, seizure, or coma.

Soma is usually taken two to three times per day and at bedtime. call your doctor’s dosing instructions very carefully. Soma is only part of a complete program of treatment for muscle pain that may also include rest, physical therapy, or other pain relief measures.

Ask your doctor how to safely stop using this medicine.

 If overdose taken of Soma?

For decontamination in cases of severe toxicity, charcoal should be considered in a hospital setting in patients with large overdoses who present early and are not demonstrating CNS depression and can protect their airway.

Basic life supports or machine oxygen mask and may be a ventilator for patient measures should be instituted as dictated by the clinical presentation of the SOMA overdose. Vomiting should not be induced because of the risk of CNS and respiratory depression, and subsequent aspiration. Bloogcirculartion support should be administered with volume infusion and vasopressor agents if needed. Seizures should be treated with intravenous benzodiazepines and the reoccurrence of seizures may be treated with phenobarbital. In cases of severe CNS depression, airway protective reflexes may be compromised and tracheal intubation should be considered for airway protection and respiratory support.

Tense, spasming muscles are often the underlying cause of back and neck pain. If the pain is severe or chronic and does not respond to over-the counter medications, muscle relaxants may be prescribed. Muscle relaxers:

  • Reduce skeletal muscle spasms
  • Relieve pain
  • Increase mobility of the affected muscles

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Muscle relaxers are used in addition to rest, physical therapy, and other measures to relieve discomfort. They are typically prescribed for short-term use to treat acute, painful musculoskeletal conditions. Muscle relaxers are occasionally prescribed for chronic pain (pain lasting longer than 3 months).